Captopril vs Citalopram

## Captopril vs Citalopram: Overview

This comparison examines the pharmacological differences between **Captopril** and **Citalopram**.

## Mechanism of Action

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

**Citalopram**: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

## Pharmacokinetics

**Half-life**: Captopril — 1.9 hours; Citalopram — 35 hours.

## Chemical Properties

**Molecular Formula**: Captopril — C9H15NO3S; Citalopram — C20H21FN2O.

**Molecular Weight**: Captopril — 217.2850 g/mol; Citalopram — 324.3920 g/mol.

**Type**: Captopril — Small molecule; Citalopram — Small molecule.