Furosemide vs Sildenafil

## Furosemide vs Sildenafil: Overview

This comparison examines the pharmacological differences between **Furosemide** and **Sildenafil**.

## Mechanism of Action

**Furosemide**: Loop diuretic inhibiting Na-K-2Cl cotransporter.

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

## Pharmacokinetics

**Half-life**: Furosemide — 2 hours; Sildenafil — 4 hours.

## Chemical Properties

**Molecular Formula**: Furosemide — C12H11ClN2O5S; Sildenafil — C22H30N6O4S.

**Molecular Weight**: Furosemide — 330.7440 g/mol; Sildenafil — 474.5800 g/mol.

**Type**: Furosemide — Small molecule; Sildenafil — Small molecule.