Irbesartan vs Spironolactone

## Irbesartan vs Spironolactone: Overview

This comparison examines the pharmacological differences between **Irbesartan** and **Spironolactone**.

## Mechanism of Action

**Irbesartan**: Selective non-competitive angiotensin II type 1 receptor antagonist.

**Spironolactone**: Mineralocorticoid receptor antagonist.

## Pharmacokinetics

**Half-life**: Irbesartan — 11-15 hours; Spironolactone — 1.4 hours.

## Chemical Properties

**Molecular Formula**: Irbesartan — C25H28N6O; Spironolactone — C24H32O4S.

**Molecular Weight**: Irbesartan — 428.5320 g/mol; Spironolactone — 416.5740 g/mol.

**Type**: Irbesartan — Small molecule; Spironolactone — Small molecule.