Losartan vs Sildenafil

## Losartan vs Sildenafil: Overview

This comparison examines the pharmacological differences between **Losartan** and **Sildenafil**.

## Mechanism of Action

**Losartan**: Angiotensin II receptor type 1 antagonist.

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

## Pharmacokinetics

**Half-life**: Losartan — 2 hours; Sildenafil — 4 hours.

## Chemical Properties

**Molecular Formula**: Losartan — C22H23ClN6O; Sildenafil — C22H30N6O4S.

**Molecular Weight**: Losartan — 422.9200 g/mol; Sildenafil — 474.5800 g/mol.

**Type**: Losartan — Small molecule; Sildenafil — Small molecule.