Ranitidine vs Tofacitinib

## Ranitidine vs Tofacitinib: Overview

This comparison examines the pharmacological differences between **Ranitidine** and **Tofacitinib**.

## Mechanism of Action

**Ranitidine**: Competitive H2 receptor antagonist.

**Tofacitinib**: Pan-JAK inhibitor with preference for JAK1 and JAK3 blocking pro-inflammatory cytokine signaling.

## Pharmacokinetics

**Half-life**: Ranitidine — 2-3 hours; Tofacitinib — 3.2 hours.

## Chemical Properties

**Molecular Formula**: Ranitidine — C13H22N4O3S; Tofacitinib — C16H20N6O.

**Molecular Weight**: Ranitidine — 314.4050 g/mol; Tofacitinib — 312.3700 g/mol.

**Type**: Ranitidine — Small molecule; Tofacitinib — Small molecule.