Sertraline vs Trazodone

## Sertraline vs Trazodone: Overview

This comparison examines the pharmacological differences between **Sertraline** and **Trazodone**.

## Mechanism of Action

**Sertraline**: Selective serotonin reuptake inhibitor (SSRI).

**Trazodone**: Serotonin antagonist and reuptake inhibitor (SARI).

## Pharmacokinetics

**Half-life**: Sertraline — 26 hours; Trazodone — 5-9 hours.

## Chemical Properties

**Molecular Formula**: Sertraline — C17H17Cl2N; Trazodone — C19H22ClN5O.

**Molecular Weight**: Sertraline — 306.2290 g/mol; Trazodone — 371.8640 g/mol.

**Type**: Sertraline — Small molecule; Trazodone — Small molecule.