Aclidinium Bromide

CHEMBL551466 Phase 4 ได้รับการอนุมัติ Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
564.6 g/mol
LogP
Phase
4

The bromide salt form of aclidinium, a long-acting inhaled bronchodilator used for the ongoing management of COPD. It is administered via a dry powder inhaler twice daily and works by keeping the airways relaxed throughout the day and night. Patients should continue to carry a short-acting rescue inhaler for sudden breathing difficulties.

น้ำหนักโมเลกุล

564.6000 g/mol

TPSA

112.00 Ų

ด้านการรักษา

กลไกการออกฤทธิ์

Activates beta-2 adrenergic receptors on bronchial smooth muscle, stimulating adenylyl cyclase and increasing intracellular cAMP. This relaxes airway smooth muscle and produces bronchodilation.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

กลไก

Activates beta-2 adrenergic receptors on bronchial smooth muscle, stimulating adenylyl cyclase and increasing intracellular cAMP. This relaxes airway smooth muscle and produces bronchodilation.

โครงสร้าง 2 มิติ

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SMILES

O=C(O[C@H]1C[N+]2(CCCOc3ccccc3)CCC1CC2)C(O)(c1cccs1)c1cccs1.[Br-]

InChI

InChI=1S/C26H30NO4S2.BrH/c28-25(26(29,23-9-4-17-32-23)24-10-5-18-33-24)31-22-19-27(14-11-20(22)12-15-27)13-6-16-30-21-7-2-1-3-8-21;/h1-5,7-10,17-18,20,22,29H,6,11-16,19H2;1H/q+1;/p-1/t20?,22-,27?;/m0./s1

Molecular Formula

C26H30BrNO4S2

HBD / HBA

1 / 7

พันธะที่หมุนได้

10

อะตอมหนัก

34

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

คำถามที่พบบ่อย

The bromide salt form of aclidinium, a long-acting inhaled bronchodilator used for the ongoing management of COPD. It is administered via a dry powder inhaler twice daily and works by keeping the airways relaxed throughout the day and night. Patients should continue to carry a short-acting rescue inhaler for sudden breathing difficulties.

Activates beta-2 adrenergic receptors on bronchial smooth muscle, stimulating adenylyl cyclase and increasing intracellular cAMP. This relaxes airway smooth muscle and produces bronchodilation.

Yes, Aclidinium Bromide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL551466. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 11519741. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

ข้อจำกัดความรับผิดชอบทางการแพทย์

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.