Belzutifan

CHEMBL4585668 Phase 4 ได้รับการอนุมัติ Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

383.3 g/mol

LogP

2.0

Phase

4

A HIF-2 alpha inhibitor that blocks the transcription factor driving the growth of certain kidney cancers and tumors associated with von Hippel-Lindau disease. It reduces the expression of growth factors that tumors need for angiogenesis.

น้ำหนักโมเลกุล

383.3000 g/mol

LogP

2.00

TPSA

95.80 Å²

Lipinski RO5

ผ่าน

ด้านการรักษา

Ovarian Cancer Pancreatic Cancer Chronic Kidney Disease Breast Cancer Prostate Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

โครงสร้าง 2 มิติ

SVG PNG

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SMILES

CS(=O)(=O)c1ccc(Oc2cc(F)cc(C#N)c2)c2c1[C@H](O)[C@H](F)[C@@H]2F

InChI

InChI=1S/C17H12F3NO4S/c1-26(23,24)12-3-2-11(13-14(12)17(22)16(20)15(13)19)25-10-5-8(7-21)4-9(18)6-10/h2-6,15-17,22H,1H3/t15-,16-,17+/m1/s1

Molecular Formula

C17H12F3NO4S

HBD / HBA

1 / 8

พันธะที่หมุนได้

3

อะตอมหนัก

26

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

คำถามที่พบบ่อย

A HIF-2 alpha inhibitor that blocks the transcription factor driving the growth of certain kidney cancers and tumors associated with von Hippel-Lindau disease. It reduces the expression of growth factors that tumors need for angiogenesis.

Yes, Belzutifan is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4585668. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 117947097. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Belzutifan บน PillFYI

โครงสร้าง

ข้อมูลด่วน

สูตร: C17H12F3NO4S
คำพ้องความหมาย: 1

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.