Cedazuridine

CHEMBL3237547 Phase 4 ได้รับการอนุมัติ Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

268.2 g/mol

LogP

-1.1

Phase

4

A cytidine deaminase inhibitor that is co-administered with the chemotherapy agent decitabine to block its degradation in the gut and increase oral bioavailability. This combination allows for oral administration of decitabine, which previously required intravenous infusion. It is used in adults with myelodysplastic syndromes and chronic myelomonocytic leukemia.

น้ำหนักโมเลกุล

268.2100 g/mol

LogP

-1.10

TPSA

102.00 Å²

Lipinski RO5

ผ่าน

ด้านการรักษา

Melanoma Lymphoma Breast Cancer Prostate Cancer Colorectal Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

โครงสร้าง 2 มิติ

SVG PNG

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SMILES

O=C1N[C@H](O)CCN1[C@@H]1O[C@H](CO)[C@@H](O)C1(F)F

InChI

InChI=1S/C9H14F2N2O5/c10-9(11)6(16)4(3-14)18-7(9)13-2-1-5(15)12-8(13)17/h4-7,14-16H,1-3H2,(H,12,17)/t4-,5-,6-,7-/m1/s1

Molecular Formula

C9H14F2N2O5

HBD / HBA

4 / 7

พันธะที่หมุนได้

2

อะตอมหนัก

18

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

คำถามที่พบบ่อย

A cytidine deaminase inhibitor that is co-administered with the chemotherapy agent decitabine to block its degradation in the gut and increase oral bioavailability. This combination allows for oral administration of decitabine, which previously required intravenous infusion. It is used in adults with myelodysplastic syndromes and chronic myelomonocytic leukemia.

Yes, Cedazuridine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3237547. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 25267009. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Cedazuridine บน PillFYI

โครงสร้าง

ข้อมูลด่วน

สูตร: C9H14F2N2O5
คำพ้องความหมาย: 1

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.