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Cholestyramine

CHEMBL1201625 Phase 4 ได้รับการอนุมัติ Unknown
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
— g/mol
LogP
—
Phase
4

A bile acid sequestrant that binds bile acids in the gastrointestinal tract, preventing their reabsorption and forcing the liver to use cholesterol to produce new bile acids, thereby lowering LDL cholesterol. It is also used to relieve pruritus caused by bile acid accumulation in cholestatic liver disease and to treat diarrhea caused by bile acid malabsorption. It can interfere with the absorption of many other drugs and fat-soluble vitamins.

ด้านการรักษา

Pancreatic Cancer Multiple Sclerosis Chronic Kidney Disease Hyperlipidemia Obesity Type 2 Diabetes Breast Cancer Cardiovascular Disease

กลไกการออกฤทธิ์

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

กลไก

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

คำถามที่พบบ่อย

A bile acid sequestrant that binds bile acids in the gastrointestinal tract, preventing their reabsorption and forcing the liver to use cholesterol to produce new bile acids, thereby lowering LDL cholesterol. It is also used to relieve pruritus caused by bile acid accumulation in cholestatic liver disease and to treat diarrhea caused by bile acid malabsorption. It can interfere with the absorption of many other drugs and fat-soluble vitamins.

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

Yes, Cholestyramine is an approved drug. It has reached clinical phase 4. It is classified as a Unknown.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201625. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.

ข้อจำกัดความรับผิดชอบทางการแพทย์

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.