Clometacin

CHEMBL13376 Phase 4 ได้รับการอนุมัติ Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
357.8 g/mol
LogP
4.0
Phase
4

A nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and reduce inflammation. It works by blocking enzymes involved in producing substances that cause pain and swelling.

น้ำหนักโมเลกุล

357.8000 g/mol

LogP

4.00

TPSA

68.50 Ų

Lipinski RO5

ผ่าน

กลไกการออกฤทธิ์

Inhibits cyclooxygenase (COX-1 and/or COX-2) enzymes, reducing the synthesis of prostaglandins and thromboxanes from arachidonic acid. This produces anti-inflammatory, analgesic, and antipyretic effects.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

กลไก

Inhibits cyclooxygenase (COX-1 and/or COX-2) enzymes, reducing the synthesis of prostaglandins and thromboxanes from arachidonic acid. This produces anti-inflammatory, analgesic, and antipyretic effects.

โครงสร้าง 2 มิติ

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SMILES

COc1ccc2c(C(=O)c3ccc(Cl)cc3)c(C)n(CC(=O)O)c2c1

InChI

InChI=1S/C19H16ClNO4/c1-11-18(19(24)12-3-5-13(20)6-4-12)15-8-7-14(25-2)9-16(15)21(11)10-17(22)23/h3-9H,10H2,1-2H3,(H,22,23)

Molecular Formula

C19H16ClNO4

HBD / HBA

1 / 4

พันธะที่หมุนได้

5

อะตอมหนัก

25

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

คำถามที่พบบ่อย

A nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and reduce inflammation. It works by blocking enzymes involved in producing substances that cause pain and swelling.

Inhibits cyclooxygenase (COX-1 and/or COX-2) enzymes, reducing the synthesis of prostaglandins and thromboxanes from arachidonic acid. This produces anti-inflammatory, analgesic, and antipyretic effects.

Yes, Clometacin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL13376. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 33176. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

ข้อจำกัดความรับผิดชอบทางการแพทย์

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.