Deutivacaftor

CHEMBL4297603 Phase 4 ได้รับการอนุมัติ Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

401.5 g/mol

LogP

5.6

Phase

4

A deuterium-modified form of ivacaftor being studied as a CFTR potentiator for cystic fibrosis. The deuterium modification is designed to improve metabolic stability and extend drug action.

น้ำหนักโมเลกุล

401.5000 g/mol

LogP

5.60

TPSA

78.40 Å²

Lipinski RO5

ผ่าน

Pharmacokinetics (PK)

Pharmacodynamics (PD)

โครงสร้าง 2 มิติ

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SMILES

[2H]C([2H])([2H])C(c1cc(C(C)(C)C)c(NC(=O)c2c[nH]c3ccccc3c2=O)cc1O)(C([2H])([2H])[2H])C([2H])([2H])[2H]

InChI

InChI=1S/C24H28N2O3/c1-23(2,3)16-11-17(24(4,5)6)20(27)12-19(16)26-22(29)15-13-25-18-10-8-7-9-14(18)21(15)28/h7-13,27H,1-6H3,(H,25,28)(H,26,29)/i4D3,5D3,6D3

Molecular Formula

C24H28N2O3

HBD / HBA

3 / 4

พันธะที่หมุนได้

4

อะตอมหนัก

29

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

คำถามที่พบบ่อย

A deuterium-modified form of ivacaftor being studied as a CFTR potentiator for cystic fibrosis. The deuterium modification is designed to improve metabolic stability and extend drug action.

Yes, Deutivacaftor is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4297603. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 71470491. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Deutivacaftor บน PillFYI

โครงสร้าง

ข้อมูลด่วน

สูตร: C24H28N2O3
คำพ้องความหมาย: 1

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.