Dipivefrin Hydrochloride

CHEMBL1200833 Phase 4 ได้รับการอนุมัติ Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
387.9 g/mol
LogP
Phase
4

The hydrochloride salt form of dipivefrin, used in ophthalmic preparations for glaucoma management. It acts as a prodrug converted to active epinephrine within the eye to lower intraocular pressure. This salt form provides stability in eye drop formulations.

น้ำหนักโมเลกุล

387.9000 g/mol

TPSA

84.90 Ų

ด้านการรักษา

กลไกการออกฤทธิ์

Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

กลไก

Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.

โครงสร้าง 2 มิติ

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SMILES

CNCC(O)c1ccc(OC(=O)C(C)(C)C)c(OC(=O)C(C)(C)C)c1.Cl

InChI

InChI=1S/C19H29NO5.ClH/c1-18(2,3)16(22)24-14-9-8-12(13(21)11-20-7)10-15(14)25-17(23)19(4,5)6;/h8-10,13,20-21H,11H2,1-7H3;1H

Molecular Formula

C19H30ClNO5

HBD / HBA

3 / 6

พันธะที่หมุนได้

9

อะตอมหนัก

26

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

คำถามที่พบบ่อย

The hydrochloride salt form of dipivefrin, used in ophthalmic preparations for glaucoma management. It acts as a prodrug converted to active epinephrine within the eye to lower intraocular pressure. This salt form provides stability in eye drop formulations.

Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.

Yes, Dipivefrin Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200833. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 71486. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

ข้อจำกัดความรับผิดชอบทางการแพทย์

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.