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Fomepizole

CHEMBL1308 Phase 4 ได้รับการอนุมัติ Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
82.1 g/mol
LogP
1.4
Phase
4

This medication works by blocking the enzyme alcohol dehydrogenase, preventing the body from converting methanol or ethylene glycol into toxic metabolites that can cause blindness, kidney failure, and death. It is used as an antidote in emergency treatment of methanol and antifreeze poisoning.

น้ำหนักโมเลกุล

82.1000 g/mol

LogP

1.40

TPSA

28.70 Ų

Lipinski RO5

ผ่าน

กลไกการออกฤทธิ์

Counteracts the effects of a specific toxin or drug overdose through competitive antagonism, enhanced elimination, or direct chemical neutralization.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

กลไก

Counteracts the effects of a specific toxin or drug overdose through competitive antagonism, enhanced elimination, or direct chemical neutralization.

โครงสร้าง 2 มิติ

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
Cc1cn[nH]c1

                

                

                
                

                    
InChI

                    
InChI=1S/C4H6N2/c1-4-2-5-6-3-4/h2-3H,1H3,(H,5,6)

                

                

                

                    
                    

                        
Molecular Formula

                        
C4H6N2

                    

                    
                    

                        
HBD / HBA

                        
1 / 1

                    

                    
                    

                        
พันธะที่หมุนได้

                        
0

                    

                    
                    
                    

                        
อะตอมหนัก

                        
6

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
คำถามที่พบบ่อย

                

                    
                    

                        
                        

                            
This medication works by blocking the enzyme alcohol dehydrogenase, preventing the body from converting methanol or ethylene glycol into toxic metabolites that can cause blindness, kidney failure, and death. It is used as an antidote in emergency treatment of methanol and antifreeze poisoning.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Counteracts the effects of a specific toxin or drug overdose through competitive antagonism, enhanced elimination, or direct chemical neutralization.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Fomepizole is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1308.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 3406.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
ข้อจำกัดความรับผิดชอบทางการแพทย์

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.