Guanabenz

CHEMBL420 Phase 4 ได้รับการอนุมัติ Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

231.1 g/mol

LogP

1.7

Phase

4

A centrally acting alpha-2 adrenergic agonist used to treat hypertension by reducing sympathetic nervous system outflow from the brain, which lowers heart rate and relaxes blood vessels. It is taken orally and was used before newer antihypertensive agents became available. Abrupt discontinuation can cause rebound hypertension and should be avoided.

น้ำหนักโมเลกุล

231.0800 g/mol

LogP

1.70

TPSA

76.80 Å²

Lipinski RO5

ผ่าน

ด้านการรักษา

Multiple Sclerosis Hypertension

Pharmacokinetics (PK)

Pharmacodynamics (PD)

โครงสร้าง 2 มิติ

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SMILES

N=C(N)N/N=C/c1c(Cl)cccc1Cl

InChI

InChI=1S/C8H8Cl2N4/c9-6-2-1-3-7(10)5(6)4-13-14-8(11)12/h1-4H,(H4,11,12,14)/b13-4+

Molecular Formula

C8H8Cl2N4

HBD / HBA

2 / 2

พันธะที่หมุนได้

2

อะตอมหนัก

14

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

คำถามที่พบบ่อย

A centrally acting alpha-2 adrenergic agonist used to treat hypertension by reducing sympathetic nervous system outflow from the brain, which lowers heart rate and relaxes blood vessels. It is taken orally and was used before newer antihypertensive agents became available. Abrupt discontinuation can cause rebound hypertension and should be avoided.

Yes, Guanabenz is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL420. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5702063. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Guanabenz บน PillFYI

โครงสร้าง

ข้อมูลด่วน

สูตร: C8H8Cl2N4
คำพ้องความหมาย: 1

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.