Guanfacine

CHEMBL862 Phase 4 ได้รับการอนุมัติ Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

246.1 g/mol

LogP

2.0

Phase

4

A selective alpha-2 adrenergic agonist used to treat attention deficit hyperactivity disorder in children and adults, and investigated for cognitive benefits in Alzheimer's disease and stress-related conditions. It works by strengthening prefrontal cortical function, improving impulse control, attention, and working memory. Unlike stimulant ADHD medications, it carries no risk of substance abuse.

น้ำหนักโมเลกุล

246.0900 g/mol

LogP

2.00

TPSA

81.50 Å²

Lipinski RO5

ผ่าน

ด้านการรักษา

Pain Management Asthma Schizophrenia Generalized Anxiety Disorder Insomnia Stroke Obesity Hypertension Major Depressive Disorder Chronic Pain Heart Failure

Pharmacokinetics (PK)

Pharmacodynamics (PD)

โครงสร้าง 2 มิติ

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SMILES

N=C(N)NC(=O)Cc1c(Cl)cccc1Cl

InChI

InChI=1S/C9H9Cl2N3O/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13/h1-3H,4H2,(H4,12,13,14,15)

Molecular Formula

C9H9Cl2N3O

HBD / HBA

2 / 1

พันธะที่หมุนได้

2

อะตอมหนัก

15

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

คำถามที่พบบ่อย

A selective alpha-2 adrenergic agonist used to treat attention deficit hyperactivity disorder in children and adults, and investigated for cognitive benefits in Alzheimer's disease and stress-related conditions. It works by strengthening prefrontal cortical function, improving impulse control, attention, and working memory. Unlike stimulant ADHD medications, it carries no risk of substance abuse.

Yes, Guanfacine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL862. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 3519. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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โครงสร้าง

ข้อมูลด่วน

สูตร: C9H9Cl2N3O
คำพ้องความหมาย: 4

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.