Hydralazine

CHEMBL276832 Phase 4 ได้รับการอนุมัติ Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

160.2 g/mol

LogP

0.7

Phase

4

A direct-acting vasodilator that relaxes arterial smooth muscle to lower blood pressure, used to treat moderate to severe hypertension, heart failure, and hypertensive emergencies during pregnancy. It is often combined with other antihypertensives as it triggers reflex tachycardia and sodium retention when used alone. Research has explored its potential role in epigenetic regulation relevant to certain cancers.

น้ำหนักโมเลกุล

160.1800 g/mol

LogP

0.70

TPSA

63.80 Å²

Lipinski RO5

ผ่าน

ด้านการรักษา

Ovarian Cancer Cardiovascular Disease Non-Small Cell Lung Cancer Epilepsy Stroke Type 2 Diabetes Hypertension Breast Cancer Heart Failure Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

โครงสร้าง 2 มิติ

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SMILES

NNc1nncc2ccccc12

InChI

InChI=1S/C8H8N4/c9-11-8-7-4-2-1-3-6(7)5-10-12-8/h1-5H,9H2,(H,11,12)

Molecular Formula

C8H8N4

HBD / HBA

2 / 4

พันธะที่หมุนได้

1

อะตอมหนัก

12

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

คำถามที่พบบ่อย

A direct-acting vasodilator that relaxes arterial smooth muscle to lower blood pressure, used to treat moderate to severe hypertension, heart failure, and hypertensive emergencies during pregnancy. It is often combined with other antihypertensives as it triggers reflex tachycardia and sodium retention when used alone. Research has explored its potential role in epigenetic regulation relevant to certain cancers.

Yes, Hydralazine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL276832. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 3637. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Hydralazine บน PillFYI

โครงสร้าง

ข้อมูลด่วน

สูตร: C8H8N4
คำพ้องความหมาย: 3

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.