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Ibandronate Sodium

CHEMBL3989569 Phase 4 ได้รับการอนุมัติ Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
359.2 g/mol
LogP
—
Phase
4

This sodium salt of ibandronate is a bisphosphonate used to treat osteoporosis in postmenopausal women and bone metastases from breast cancer. It reduces bone resorption by inhibiting osteoclasts, which helps to strengthen bones and reduce fracture risk. Monthly oral tablets or quarterly intravenous infusions are available.

น้ำหนักโมเลกุล

359.2300 g/mol

TPSA

142.00 Ų

ด้านการรักษา

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Pain Management Non-Small Cell Lung Cancer Rheumatoid Arthritis Osteoporosis Systemic Lupus Erythematosus Type 2 Diabetes Breast Cancer Chronic Pain Prostate Cancer Colorectal Cancer

กลไกการออกฤทธิ์

Binds to hydroxyapatite crystals in bone, inhibiting osteoclast-mediated bone resorption by disrupting the mevalonate pathway within osteoclasts. This reduces bone turnover and increases bone mineral density.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

กลไก

Binds to hydroxyapatite crystals in bone, inhibiting osteoclast-mediated bone resorption by disrupting the mevalonate pathway within osteoclasts. This reduces bone turnover and increases bone mineral density.

โครงสร้าง 2 มิติ

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CCCCCN(C)CCC(O)(P(=O)([O-])O)P(=O)(O)O.O.[Na+]

                

                

                
                

                    
InChI

                    
InChI=1S/C9H23NO7P2.Na.H2O/c1-3-4-5-7-10(2)8-6-9(11,18(12,13)14)19(15,16)17;;/h11H,3-8H2,1-2H3,(H2,12,13,14)(H2,15,16,17);;1H2/q;+1;/p-1

                

                

                

                    
                    

                        
Molecular Formula

                        
C9H24NNaO8P2

                    

                    
                    

                        
HBD / HBA

                        
5 / 9

                    

                    
                    

                        
พันธะที่หมุนได้

                        
9

                    

                    
                    
                    

                        
อะตอมหนัก

                        
21

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
คำถามที่พบบ่อย

                

                    
                    

                        
                        

                            
This sodium salt of ibandronate is a bisphosphonate used to treat osteoporosis in postmenopausal women and bone metastases from breast cancer. It reduces bone resorption by inhibiting osteoclasts, which helps to strengthen bones and reduce fracture risk. Monthly oral tablets or quarterly intravenous infusions are available.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Binds to hydroxyapatite crystals in bone, inhibiting osteoclast-mediated bone resorption by disrupting the mevalonate pathway within osteoclasts. This reduces bone turnover and increases bone mineral density.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Ibandronate Sodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL3989569.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 23663991.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
ข้อจำกัดความรับผิดชอบทางการแพทย์

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.