Ifosfamide

CHEMBL1024 Phase 4 ได้รับการอนุมัติ Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

261.1 g/mol

LogP

0.9

Phase

4

This alkylating chemotherapy agent works by cross-linking DNA strands within cancer cells, preventing them from replicating. It is used to treat a variety of cancers including sarcomas, testicular cancer, and lymphomas. A key concern is ifosfamide-induced hemorrhagic cystitis (bladder irritation), which is prevented by co-administering the protective agent mesna.

น้ำหนักโมเลกุล

261.0800 g/mol

LogP

0.90

TPSA

41.60 Å²

Lipinski RO5

ผ่าน

ด้านการรักษา

Melanoma Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Non-Small Cell Lung Cancer Lymphoma Breast Cancer Prostate Cancer Colorectal Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

โครงสร้าง 2 มิติ

SVG PNG

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SMILES

O=P1(NCCCl)OCCCN1CCCl

InChI

InChI=1S/C7H15Cl2N2O2P/c8-2-4-10-14(12)11(6-3-9)5-1-7-13-14/h1-7H2,(H,10,12)

Molecular Formula

C7H15Cl2N2O2P

HBD / HBA

1 / 4

พันธะที่หมุนได้

5

อะตอมหนัก

14

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

คำถามที่พบบ่อย

This alkylating chemotherapy agent works by cross-linking DNA strands within cancer cells, preventing them from replicating. It is used to treat a variety of cancers including sarcomas, testicular cancer, and lymphomas. A key concern is ifosfamide-induced hemorrhagic cystitis (bladder irritation), which is prevented by co-administering the protective agent mesna.

Yes, Ifosfamide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1024. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 3690. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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โครงสร้าง

ข้อมูลด่วน

สูตร: C7H15Cl2N2O2P
คำพ้องความหมาย: 1

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.