Ivabradine Hydrochloride

CHEMBL2145077 Phase 4 ได้รับการอนุมัติ Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

505.0 g/mol

LogP

—

Phase

4

This hydrochloride salt of ivabradine is the commercially available formulation used to reduce heart rate in patients with stable coronary artery disease and heart failure. It acts specifically on the sinoatrial node's pacemaker channel to slow heart rate, reducing the oxygen demand of the heart. Visual side effects (phosphenes) can occur but are usually transient.

น้ำหนักโมเลกุล

505.0000 g/mol

TPSA

60.50 Å²

Pharmacokinetics (PK)

Pharmacodynamics (PD)

โครงสร้าง 2 มิติ

SVG PNG

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SMILES

COc1cc2c(cc1OC)CC(=O)N(CCCN(C)C[C@H]1Cc3cc(OC)c(OC)cc31)CC2.Cl

InChI

InChI=1S/C27H36N2O5.ClH/c1-28(17-21-11-20-14-25(33-4)26(34-5)16-22(20)21)8-6-9-29-10-7-18-12-23(31-2)24(32-3)13-19(18)15-27(29)30;/h12-14,16,21H,6-11,15,17H2,1-5H3;1H/t21-;/m1./s1

Molecular Formula

C27H37ClN2O5

HBD / HBA

1 / 6

พันธะที่หมุนได้

10

อะตอมหนัก

35

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

คำถามที่พบบ่อย

This hydrochloride salt of ivabradine is the commercially available formulation used to reduce heart rate in patients with stable coronary artery disease and heart failure. It acts specifically on the sinoatrial node's pacemaker channel to slow heart rate, reducing the oxygen demand of the heart. Visual side effects (phosphenes) can occur but are usually transient.

Yes, Ivabradine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2145077. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 3045381. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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โครงสร้าง

ข้อมูลด่วน

สูตร: C27H37ClN2O5

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.