Peficitinib Hydrobromide

CHEMBL3137329 Phase 4 ได้รับการอนุมัติ Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

407.3 g/mol

LogP

—

Phase

4

A hydrobromide salt form of peficitinib, a pan-JAK inhibitor approved in Japan to treat rheumatoid arthritis by blocking the JAK signaling pathway that drives joint inflammation. It reduces cytokine-mediated inflammation and slows joint damage.

น้ำหนักโมเลกุล

407.3000 g/mol

TPSA

104.00 Å²

Pharmacokinetics (PK)

Pharmacodynamics (PD)

โครงสร้าง 2 มิติ

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SMILES

Br.NC(=O)c1cnc2[nH]ccc2c1N[C@@H]1[C@@H]2CC3C[C@H]1C[C@@](O)(C3)C2

InChI

InChI=1S/C18H22N4O2.BrH/c19-16(23)13-8-21-17-12(1-2-20-17)15(13)22-14-10-3-9-4-11(14)7-18(24,5-9)6-10;/h1-2,8-11,14,24H,3-7H2,(H2,19,23)(H2,20,21,22);1H/t9?,10-,11+,14-,18-;

Molecular Formula

C18H23BrN4O2

HBD / HBA

5 / 4

พันธะที่หมุนได้

3

อะตอมหนัก

25

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

คำถามที่พบบ่อย

A hydrobromide salt form of peficitinib, a pan-JAK inhibitor approved in Japan to treat rheumatoid arthritis by blocking the JAK signaling pathway that drives joint inflammation. It reduces cytokine-mediated inflammation and slows joint damage.

Yes, Peficitinib Hydrobromide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3137329. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 67998300. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Peficitinib Hydrobromide บน PillFYI

โครงสร้าง

ข้อมูลด่วน

สูตร: C18H23BrN4O2

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.