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What is Polyestradiol Phosphate used for?

Polyestradiol phosphate is a polymeric esterified form of estradiol that is slowly hydrolyzed after intramuscular injection to release free estradiol, providing long-lasting estrogenic activity as a depot preparation. It is used in the hormonal treatment of prostate cancer to suppress testosterone levels, and has also been investigated in breast cancer and leukemia treatment.

Is Polyestradiol Phosphate an approved drug?

Yes, Polyestradiol Phosphate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

• ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201477. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.