Rose Bengal Sodium I 131
Rose bengal sodium I-131 is a radioiodinated hepatobiliary imaging agent in which the rose bengal dye is labeled with iodine-131 for scintigraphic evaluation of liver and biliary tract function. It is selectively taken up by hepatocytes and excreted into bile, allowing assessment of hepatic clearance and biliary patency. The compound has also been investigated in experimental oncology for targeted radiotherapy of breast and colorectal cancers.
น้ำหนักโมเลกุล
1019.6000 g/mol
TPSA
76.00 Ų
ด้านการรักษา
Pharmacokinetics (PK)
Pharmacodynamics (PD)
โครงสร้าง 2 มิติ
Cite this structure
Embed this structure
SMILES
O=C([O-])c1c(Cl)c(Cl)c(Cl)c(Cl)c1-c1c2cc([131I])c(=O)c(I)c-2oc2c(I)c([O-])c([131I])cc12.[Na+].[Na+]
InChI
InChI=1S/C20H4Cl4I4O5.2Na/c21-10-8(9(20(31)32)11(22)13(24)12(10)23)7-3-1-5(25)16(29)14(27)18(3)33-19-4(7)2-6(26)17(30)15(19)28;;/h1-2,29H,(H,31,32);;/q;2*+1/p-2/i25+4,26+4;;
Molecular Formula
C20H4Cl4I4Na2O5+2
HBD / HBA
2 / 5
พันธะที่หมุนได้
0
อะตอมหนัก
35
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
คำถามที่พบบ่อย
Rose bengal sodium I-131 is a radioiodinated hepatobiliary imaging agent in which the rose bengal dye is labeled with iodine-131 for scintigraphic evaluation of liver and biliary tract function. It is selectively taken up by hepatocytes and excreted into bile, allowing assessment of hepatic clearance and biliary patency. The compound has also been investigated in experimental oncology for targeted radiotherapy of breast and colorectal cancers.
Yes, Rose Bengal Sodium I 131 is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3989461. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 22239536. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
ข้อจำกัดความรับผิดชอบทางการแพทย์
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
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