Rose Bengal Sodium I 131

CHEMBL3989461 Phase 4 ได้รับการอนุมัติ Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
1019.6 g/mol
LogP
Phase
4

Rose bengal sodium I-131 is a radioiodinated hepatobiliary imaging agent in which the rose bengal dye is labeled with iodine-131 for scintigraphic evaluation of liver and biliary tract function. It is selectively taken up by hepatocytes and excreted into bile, allowing assessment of hepatic clearance and biliary patency. The compound has also been investigated in experimental oncology for targeted radiotherapy of breast and colorectal cancers.

น้ำหนักโมเลกุล

1019.6000 g/mol

TPSA

76.00 Ų

ด้านการรักษา

Pharmacokinetics (PK)

Pharmacodynamics (PD)

โครงสร้าง 2 มิติ

SVG PNG

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SMILES

O=C([O-])c1c(Cl)c(Cl)c(Cl)c(Cl)c1-c1c2cc([131I])c(=O)c(I)c-2oc2c(I)c([O-])c([131I])cc12.[Na+].[Na+]

InChI

InChI=1S/C20H4Cl4I4O5.2Na/c21-10-8(9(20(31)32)11(22)13(24)12(10)23)7-3-1-5(25)16(29)14(27)18(3)33-19-4(7)2-6(26)17(30)15(19)28;;/h1-2,29H,(H,31,32);;/q;2*+1/p-2/i25+4,26+4;;

Molecular Formula

C20H4Cl4I4Na2O5+2

HBD / HBA

2 / 5

พันธะที่หมุนได้

0

อะตอมหนัก

35

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

คำถามที่พบบ่อย

Rose bengal sodium I-131 is a radioiodinated hepatobiliary imaging agent in which the rose bengal dye is labeled with iodine-131 for scintigraphic evaluation of liver and biliary tract function. It is selectively taken up by hepatocytes and excreted into bile, allowing assessment of hepatic clearance and biliary patency. The compound has also been investigated in experimental oncology for targeted radiotherapy of breast and colorectal cancers.

Yes, Rose Bengal Sodium I 131 is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3989461. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 22239536. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.