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Sodium Monofluorophosphate

CHEMBL1908359 Phase 4 ได้รับการอนุมัติ Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
144.0 g/mol
LogP
—
Phase
4

Sodium monofluorophosphate is a fluoride compound used as an active ingredient in fluoride toothpastes for caries prevention, releasing fluoride ions after enzymatic hydrolysis in the oral cavity to promote remineralization of tooth enamel. Unlike sodium fluoride, it requires hydrolysis by salivary phosphatases before fluoride ions become bioavailable for enamel incorporation. It is widely used in oral hygiene products as an alternative fluoride source.

น้ำหนักโมเลกุล

143.9500 g/mol

TPSA

63.20 Ų

กลไกการออกฤทธิ์

Provides an essential mineral element required for numerous enzymatic reactions, structural proteins, and physiological processes. Supplementation addresses deficiency states.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

กลไก

Provides an essential mineral element required for numerous enzymatic reactions, structural proteins, and physiological processes. Supplementation addresses deficiency states.

โครงสร้าง 2 มิติ

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
O=P([O-])([O-])F.[Na+].[Na+]

                

                

                
                

                    
InChI

                    
InChI=1S/FH2O3P.2Na/c1-5(2,3)4;;/h(H2,2,3,4);;/q;2*+1/p-2

                

                

                

                    
                    

                        
Molecular Formula

                        
FNa2O3P

                    

                    
                    

                        
HBD / HBA

                        
- / 4

                    

                    
                    

                        
พันธะที่หมุนได้

                        
0

                    

                    
                    
                    

                        
อะตอมหนัก

                        
7

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
คำถามที่พบบ่อย

                

                    
                    

                        
                        

                            
Sodium monofluorophosphate is a fluoride compound used as an active ingredient in fluoride toothpastes for caries prevention, releasing fluoride ions after enzymatic hydrolysis in the oral cavity to promote remineralization of tooth enamel. Unlike sodium fluoride, it requires hydrolysis by salivary phosphatases before fluoride ions become bioavailable for enamel incorporation. It is widely used in oral hygiene products as an alternative fluoride source.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Provides an essential mineral element required for numerous enzymatic reactions, structural proteins, and physiological processes. Supplementation addresses deficiency states.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Sodium Monofluorophosphate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1908359.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 24266.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
ข้อจำกัดความรับผิดชอบทางการแพทย์

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.