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Triamterene

CHEMBL585 Phase 4 ได้รับการอนุมัติ Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
253.3 g/mol
LogP
1.0
Phase
4

This potassium-sparing diuretic helps the kidneys remove excess fluid from the body without causing the loss of potassium, and is used to treat fluid retention (edema) related to heart failure, liver disease, or kidney disease, often in combination with another diuretic. Unlike most diuretics that cause potassium loss, triamterene helps retain potassium, so potassium supplements or potassium-rich foods should be avoided. Kidney function and potassium levels need regular monitoring.

น้ำหนักโมเลกุล

253.2600 g/mol

LogP

1.00

TPSA

130.00 Ų

Lipinski RO5

ผ่าน

ด้านการรักษา

Hypertension Cardiovascular Disease

Pharmacokinetics (PK)

Pharmacodynamics (PD)

โครงสร้าง 2 มิติ

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
Nc1nc(N)c2nc(-c3ccccc3)c(N)nc2n1

                

                

                
                

                    
InChI

                    
InChI=1S/C12H11N7/c13-9-7(6-4-2-1-3-5-6)16-8-10(14)18-12(15)19-11(8)17-9/h1-5H,(H6,13,14,15,17,18,19)

                

                

                

                    
                    

                        
Molecular Formula

                        
C12H11N7

                    

                    
                    

                        
HBD / HBA

                        
3 / 7

                    

                    
                    

                        
พันธะที่หมุนได้

                        
1

                    

                    
                    
                    

                        
อะตอมหนัก

                        
19

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
คำถามที่พบบ่อย

                

                    
                    

                        
                        

                            
This potassium-sparing diuretic helps the kidneys remove excess fluid from the body without causing the loss of potassium, and is used to treat fluid retention (edema) related to heart failure, liver disease, or kidney disease, often in combination with another diuretic. Unlike most diuretics that cause potassium loss, triamterene helps retain potassium, so potassium supplements or potassium-rich foods should be avoided. Kidney function and potassium levels need regular monitoring.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Triamterene is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL585.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5546.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
ข้อจำกัดความรับผิดชอบทางการแพทย์

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.