💊 ยา A-Z 🧬 เป้าหมาย 🛠 เครื่องมือ 📚 คู่มือ
ยาทั้งหมด หมวดหมู่ยา ด้านการรักษา ผลข้างเคียง
คู่มือ อภิธานศัพท์ ไทม์ไลน์
การเปรียบเทียบ เส้นทางของยา กลุ่มยา
🇺🇸 English 🇰🇷 한국어 🇯🇵 日本語 🇨🇳 中文简体 🇪🇸 Español 🇧🇷 Português 🇮🇳 हिन्दी 🇸🇦 العربية 🇫🇷 Français 🇷🇺 Русский 🇩🇪 Deutsch 🇹🇷 Türkçe 🇻🇳 Tiếng Việt 🇮🇩 Bahasa Indonesia 🇹🇭 ไทย

Triclosan

CHEMBL849 Phase 4 ได้รับการอนุมัติ Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
289.5 g/mol
LogP
5.0
Phase
4

Triclosan is a chlorinated aromatic compound with broad-spectrum antimicrobial activity that inhibits bacterial enoyl-acyl carrier protein reductase (ENR, FabI), a key enzyme in bacterial fatty acid synthesis required for cell membrane integrity and growth. It is widely used in consumer products (toothpastes, surgical scrubs, antimicrobial soaps) and has been investigated for treatment of infectious diseases and potential antiproliferative effects in cancer cell lines. Regulatory restrictions have been placed on triclosan in rinse-off consumer products due to concerns about endocrine disruption, antimicrobial resistance selection, and lack of proven clinical benefit.

น้ำหนักโมเลกุล

289.5000 g/mol

LogP

5.00

TPSA

29.50 Ų

Lipinski RO5

ผ่าน

ด้านการรักษา

Infectious Disease Psoriasis Breast Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

โครงสร้าง 2 มิติ

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1Cl

                

                

                
                

                    
InChI

                    
InChI=1S/C12H7Cl3O2/c13-7-1-3-11(9(15)5-7)17-12-4-2-8(14)6-10(12)16/h1-6,16H

                

                

                

                    
                    

                        
Molecular Formula

                        
C12H7Cl3O2

                    

                    
                    

                        
HBD / HBA

                        
1 / 2

                    

                    
                    

                        
พันธะที่หมุนได้

                        
2

                    

                    
                    
                    

                        
อะตอมหนัก

                        
17

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
คำถามที่พบบ่อย

                

                    
                    

                        
                        

                            
Triclosan is a chlorinated aromatic compound with broad-spectrum antimicrobial activity that inhibits bacterial enoyl-acyl carrier protein reductase (ENR, FabI), a key enzyme in bacterial fatty acid synthesis required for cell membrane integrity and growth. It is widely used in consumer products (toothpastes, surgical scrubs, antimicrobial soaps) and has been investigated for treatment of infectious diseases and potential antiproliferative effects in cancer cell lines. Regulatory restrictions have been placed on triclosan in rinse-off consumer products due to concerns about endocrine disruption, …

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Triclosan is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL849.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5564.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
ข้อจำกัดความรับผิดชอบทางการแพทย์

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.