Tridihexethyl
Tridihexethyl is a quaternary ammonium anticholinergic agent that competitively blocks muscarinic acetylcholine receptors in smooth muscle, exocrine glands, and the CNS, reducing gastrointestinal motility and secretions for the treatment of peptic ulcer disease, irritable bowel syndrome, and functional gastrointestinal disorders. As a quaternary ammonium compound, it has limited CNS penetration, reducing central anticholinergic adverse effects compared to tertiary amine anticholinergics. Its primary effects are on peripheral muscarinic receptors in the GI tract.
น้ำหนักโมเลกุล
318.5000 g/mol
LogP
4.80
TPSA
20.20 Ų
Lipinski RO5
ผ่าน
Pharmacokinetics (PK)
Pharmacodynamics (PD)
โครงสร้าง 2 มิติ
Cite this structure
Embed this structure
SMILES
CC[N+](CC)(CC)CCC(O)(c1ccccc1)C1CCCCC1
InChI
InChI=1S/C21H36NO/c1-4-22(5-2,6-3)18-17-21(23,19-13-9-7-10-14-19)20-15-11-8-12-16-20/h7,9-10,13-14,20,23H,4-6,8,11-12,15-18H2,1-3H3/q+1
Molecular Formula
C21H36NO+
HBD / HBA
1 / 1
พันธะที่หมุนได้
8
อะตอมหนัก
23
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
คำถามที่พบบ่อย
Tridihexethyl is a quaternary ammonium anticholinergic agent that competitively blocks muscarinic acetylcholine receptors in smooth muscle, exocrine glands, and the CNS, reducing gastrointestinal motility and secretions for the treatment of peptic ulcer disease, irritable bowel syndrome, and functional gastrointestinal disorders. As a quaternary ammonium compound, it has limited CNS penetration, reducing central anticholinergic adverse effects compared to tertiary amine anticholinergics. Its primary effects are on peripheral muscarinic receptors in the GI tract.
Yes, Tridihexethyl is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201354. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 20299. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
ข้อจำกัดความรับผิดชอบทางการแพทย์
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
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