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Urofollitropin

CHEMBL1201520 Phase 4 ได้รับการอนุมัติ Unknown
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
980.2 g/mol
LogP
-1.5
Phase
4

Urofollitropin is a purified preparation of follicle-stimulating hormone (FSH) extracted and purified from the urine of postmenopausal women, used to stimulate follicular development and ovulation in the treatment of infertility. It is used in assisted reproductive technologies to stimulate multiple follicle development for egg retrieval and in ovulation induction for anovulatory infertility. Its urinary origin distinguishes it from recombinant FSH preparations (follitropin alfa and beta).

น้ำหนักโมเลกุล

980.2000 g/mol

LogP

-1.50

TPSA

427.00 Ų

Lipinski RO5

ไม่ผ่าน

กลไกการออกฤทธิ์

As a recombinant protein, it replicates the function of the naturally occurring human protein, supplementing or replacing deficient endogenous production to restore normal physiological activity.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

กลไก

As a recombinant protein, it replicates the function of the naturally occurring human protein, supplementing or replacing deficient endogenous production to restore normal physiological activity.

SMILES

CC[C@@H](C)C1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](CSSC[C@H](C(=O)N[C@@H](C(=O)N1)CC2=CC=C(C=C2)O)N)C(=O)N3CCC[C@@H]3C(=O)N[C@H](CC(C)C)C(=O)NCC(=O)N)CC(=O)N)[C@H](C)O

InChI

InChI=1S/C42H65N11O12S2/c1-6-21(4)33-40(63)52-34(22(5)54)41(64)49-28(16-31(44)56)37(60)50-29(19-67-66-18-25(43)35(58)47-27(38(61)51-33)15-23-9-11-24(55)12-10-23)42(65)53-13-7-8-30(53)39(62)48-26(14-20(2)3)36(59)46-17-32(45)57/h9-12,20-22,25-30,33-34,54-55H,6-8,13-19,43H2,1-5H3,(H2,44,56)(H2,45,57)(H,46,59)(H,47,58)(H,48,62)(H,49,64)(H,50,60)(H,51,61)(H,52,63)/t21-,22+,25-,26-,27-,28+,29-,30-,33?,34+/m1/s1

Molecular Formula

C42H65N11O12S2

HBD / HBA

12 / 15

พันธะที่หมุนได้

15

อะตอมหนัก

67

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

คำถามที่พบบ่อย

Urofollitropin is a purified preparation of follicle-stimulating hormone (FSH) extracted and purified from the urine of postmenopausal women, used to stimulate follicular development and ovulation in the treatment of infertility. It is used in assisted reproductive technologies to stimulate multiple follicle development for egg retrieval and in ovulation induction for anovulatory infertility. Its urinary origin distinguishes it from recombinant FSH preparations (follitropin alfa and beta).

As a recombinant protein, it replicates the function of the naturally occurring human protein, supplementing or replacing deficient endogenous production to restore normal physiological activity.

Yes, Urofollitropin is an approved drug. It has reached clinical phase 4. It is classified as a Unknown.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201520. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 73759969. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

ข้อจำกัดความรับผิดชอบทางการแพทย์

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.