💊 ยา A-Z 🧬 เป้าหมาย 🛠 เครื่องมือ 📚 คู่มือ
ยาทั้งหมด หมวดหมู่ยา ด้านการรักษา ผลข้างเคียง
คู่มือ อภิธานศัพท์ ไทม์ไลน์
การเปรียบเทียบ เส้นทางของยา กลุ่มยา
🇺🇸 English 🇰🇷 한국어 🇯🇵 日本語 🇨🇳 中文简体 🇪🇸 Español 🇧🇷 Português 🇮🇳 हिन्दी 🇸🇦 العربية 🇫🇷 Français 🇷🇺 Русский 🇩🇪 Deutsch 🇹🇷 Türkçe 🇻🇳 Tiếng Việt 🇮🇩 Bahasa Indonesia 🇹🇭 ไทย

Vorinostat

CHEMBL98 Phase 4 ได้รับการอนุมัติ Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
264.3 g/mol
LogP
1.9
Phase
4

This histone deacetylase (HDAC) inhibitor is used to treat cutaneous T-cell lymphoma (CTCL), a type of cancer affecting the skin, in patients whose disease has progressed or returned during or after two prior treatments. It works by blocking enzymes that regulate gene expression in cancer cells, promoting their death. Common side effects include fatigue, nausea, and blood clots, and patients need regular monitoring of blood counts and electrolytes.

น้ำหนักโมเลกุล

264.3200 g/mol

LogP

1.90

TPSA

78.40 Ų

Lipinski RO5

ผ่าน

ด้านการรักษา

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Non-Small Cell Lung Cancer Rheumatoid Arthritis Epilepsy Schizophrenia Melanoma Lymphoma Breast Cancer HIV/AIDS Heart Failure Prostate Cancer Colorectal Cancer Leukemia

กลไกการออกฤทธิ์

Provides essential ions for maintaining fluid balance, nerve conduction, muscle contraction, and acid-base homeostasis. Supplementation corrects electrolyte imbalances.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

กลไก

Provides essential ions for maintaining fluid balance, nerve conduction, muscle contraction, and acid-base homeostasis. Supplementation corrects electrolyte imbalances.

โครงสร้าง 2 มิติ

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
O=C(CCCCCCC(=O)Nc1ccccc1)NO

                

                

                
                

                    
InChI

                    
InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)

                

                

                

                    
                    

                        
Molecular Formula

                        
C14H20N2O3

                    

                    
                    

                        
HBD / HBA

                        
3 / 3

                    

                    
                    

                        
พันธะที่หมุนได้

                        
8

                    

                    
                    
                    

                        
อะตอมหนัก

                        
19

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
คำถามที่พบบ่อย

                

                    
                    

                        
                        

                            
This histone deacetylase (HDAC) inhibitor is used to treat cutaneous T-cell lymphoma (CTCL), a type of cancer affecting the skin, in patients whose disease has progressed or returned during or after two prior treatments. It works by blocking enzymes that regulate gene expression in cancer cells, promoting their death. Common side effects include fatigue, nausea, and blood clots, and patients need regular monitoring of blood counts and electrolytes.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Provides essential ions for maintaining fluid balance, nerve conduction, muscle contraction, and acid-base homeostasis. Supplementation corrects electrolyte imbalances.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Vorinostat is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL98.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5311.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
ข้อจำกัดความรับผิดชอบทางการแพทย์

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.