Acetaminophen vs Celecoxib

## Acetaminophen vs Celecoxib: Overview

This comparison examines the pharmacological differences between **Acetaminophen** and **Celecoxib**.

## Mechanism of Action

**Acetaminophen**: Inhibits prostaglandin synthesis in the CNS and peripherally blocks pain impulse generation.

**Celecoxib**: Selective COX-2 inhibitor.

## Pharmacokinetics

**Half-life**: Acetaminophen — 1-4 hours; Celecoxib — 11 hours.

## Chemical Properties

**Molecular Formula**: Acetaminophen — C8H9NO2; Celecoxib — C17H14F3N3O2S.

**Molecular Weight**: Acetaminophen — 151.1630 g/mol; Celecoxib — 381.3730 g/mol.

**Type**: Acetaminophen — Small molecule; Celecoxib — Small molecule.