Acyclovir vs Fluconazole

## Acyclovir vs Fluconazole: Overview

This comparison examines the pharmacological differences between **Acyclovir** and **Fluconazole**.

## Mechanism of Action

**Acyclovir**: Guanosine analogue inhibiting viral DNA polymerase.

**Fluconazole**: Inhibits fungal CYP51 (lanosterol 14-alpha-demethylase).

## Pharmacokinetics

**Half-life**: Acyclovir — 2.5-3.3 hours; Fluconazole — 30 hours.

## Chemical Properties

**Molecular Formula**: Acyclovir — C8H11N5O3; Fluconazole — C13H12F2N6O.

**Molecular Weight**: Acyclovir — 225.2050 g/mol; Fluconazole — 306.2710 g/mol.

**Type**: Acyclovir — Small molecule; Fluconazole — Small molecule.