Captopril vs Edoxaban

## Captopril vs Edoxaban: Overview

This comparison examines the pharmacological differences between **Captopril** and **Edoxaban**.

## Mechanism of Action

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

**Edoxaban**: Direct, selective inhibitor of Factor Xa preventing thrombin generation and clot formation.

## Pharmacokinetics

**Half-life**: Captopril — 1.9 hours; Edoxaban — 10-14 hours.

## Chemical Properties

**Molecular Formula**: Captopril — C9H15NO3S; Edoxaban — C24H30ClN7O4S.

**Molecular Weight**: Captopril — 217.2850 g/mol; Edoxaban — 548.0530 g/mol.

**Type**: Captopril — Small molecule; Edoxaban — Small molecule.