Celecoxib vs Diphenhydramine

## Celecoxib vs Diphenhydramine: Overview

This comparison examines the pharmacological differences between **Celecoxib** and **Diphenhydramine**.

## Mechanism of Action

**Celecoxib**: Selective COX-2 inhibitor.

**Diphenhydramine**: First-generation H1 antihistamine with anticholinergic properties.

## Pharmacokinetics

**Half-life**: Celecoxib — 11 hours; Diphenhydramine — 2-8 hours.

## Chemical Properties

**Molecular Formula**: Celecoxib — C17H14F3N3O2S; Diphenhydramine — C17H21NO.

**Molecular Weight**: Celecoxib — 381.3730 g/mol; Diphenhydramine — 255.3550 g/mol.

**Type**: Celecoxib — Small molecule; Diphenhydramine — Small molecule.