Cyclosporine vs Hydroxychloroquine

## Cyclosporine vs Hydroxychloroquine: Overview

This comparison examines the pharmacological differences between **Cyclosporine** and **Hydroxychloroquine**.

## Mechanism of Action

**Cyclosporine**: Calcineurin inhibitor suppressing T-cell activation.

**Hydroxychloroquine**: Accumulates in lysosomes raising pH; inhibits toll-like receptor signaling.

## Pharmacokinetics

**Half-life**: Cyclosporine — 6-12 hours; Hydroxychloroquine — 40-50 days.

## Chemical Properties

**Molecular Formula**: Cyclosporine — C62H111N11O12; Hydroxychloroquine — C18H26ClN3O.

**Molecular Weight**: Cyclosporine — 1202.6100 g/mol; Hydroxychloroquine — 335.8720 g/mol.

**Type**: Cyclosporine — Protein; Hydroxychloroquine — Small molecule.