Dexamethasone vs Methylprednisolone

## Dexamethasone vs Methylprednisolone: Overview

This comparison examines the pharmacological differences between **Dexamethasone** and **Methylprednisolone**.

## Mechanism of Action

**Dexamethasone**: Potent synthetic glucocorticoid.

**Methylprednisolone**: Intermediate-acting synthetic glucocorticoid.

## Pharmacokinetics

**Half-life**: Dexamethasone — 36-54 hours; Methylprednisolone — 18-36 hours.

## Chemical Properties

**Molecular Formula**: Dexamethasone — C22H29FO5; Methylprednisolone — C22H30O5.

**Molecular Weight**: Dexamethasone — 392.4610 g/mol; Methylprednisolone — 374.4710 g/mol.

**Type**: Dexamethasone — Small molecule; Methylprednisolone — Small molecule.