Alitretinoin
A retinoid medication related to vitamin A that activates nuclear receptors to normalize skin cell growth and reduce inflammation, used to treat severe chronic hand eczema that has not responded to other treatments. It is also studied in certain skin cancers like Kaposi's sarcoma, where it helps regulate abnormal cell proliferation.
Moleküler Ağırlık
300,4000 g/mol
LogP
6,30
TPSA
37,30 Ų
Lipinski RO5
Geçer
Terapötik Alanlar
Etki Mekanizması
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
2D Yapı
Cite this structure
Embed this structure
SMILES
CC1=C(/C=C/C(C)=C\C=C\C(C)=C\C(=O)O)C(C)(C)CCC1
InChI
InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8-,16-14+
Molecular Formula
C20H28O2
HBD / HBA
1 / 2
Döndürülebilir Bağlar
5
Ağır Atomlar
22
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
A retinoid medication related to vitamin A that activates nuclear receptors to normalize skin cell growth and reduce inflammation, used to treat severe chronic hand eczema that has not responded to other treatments. It is also studied in certain skin cancers like Kaposi's sarcoma, where it helps regulate abnormal cell proliferation.
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
Yes, Alitretinoin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL705. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 449171. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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