Benztropine
An anticholinergic medication used to manage symptoms of Parkinson's disease, including tremors, stiffness, and abnormal movements. It is also used to treat movement-related side effects caused by certain antipsychotic medications. It works by restoring the balance of chemicals in the brain.
Moleküler Ağırlık
307,4000 g/mol
LogP
4,50
TPSA
12,50 Ų
Lipinski RO5
Geçer
Terapötik Alanlar
Etki Mekanizması
Blocks dopamine D2 receptors in the mesolimbic pathway, reducing excessive dopaminergic neurotransmission associated with psychotic symptoms. Many also antagonize serotonin 5-HT2A receptors, which may improve negative symptoms and reduce extrapyramidal side effects.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Blocks dopamine D2 receptors in the mesolimbic pathway, reducing excessive dopaminergic neurotransmission associated with psychotic symptoms. Many also antagonize serotonin 5-HT2A receptors, which may improve negative symptoms and reduce extrapyramidal …
2D Yapı
Cite this structure
Embed this structure
SMILES
CN1[C@@H]2CC[C@H]1C[C@@H](OC(c1ccccc1)c1ccccc1)C2
InChI
InChI=1S/C21H25NO/c1-22-18-12-13-19(22)15-20(14-18)23-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18-21H,12-15H2,1H3/t18-,19+,20+
Molecular Formula
C21H25NO
HBD / HBA
- / 2
Döndürülebilir Bağlar
4
Ağır Atomlar
23
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
An anticholinergic medication used to manage symptoms of Parkinson's disease, including tremors, stiffness, and abnormal movements. It is also used to treat movement-related side effects caused by certain antipsychotic medications. It works by restoring the balance of chemicals in the brain.
Blocks dopamine D2 receptors in the mesolimbic pathway, reducing excessive dopaminergic neurotransmission associated with psychotic symptoms. Many also antagonize serotonin 5-HT2A receptors, which may improve negative symptoms and reduce extrapyramidal side effects.
Yes, Benztropine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201203. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 1201549. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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