Brincidofovir
An oral antiviral medication used for the treatment of human smallpox disease caused by variola virus. It is a lipid conjugate of cidofovir that improves oral bioavailability while reducing kidney toxicity associated with cidofovir itself. It is considered a medical countermeasure for bioterrorism-related smallpox exposure.
Moleküler Ağırlık
561,7000 g/mol
LogP
4,90
TPSA
144,00 Ų
Lipinski RO5
Geçer
Terapötik Alanlar
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D Yapı
Cite this structure
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SMILES
CCCCCCCCCCCCCCCCOCCCOP(=O)(O)CO[C@H](CO)Cn1ccc(N)nc1=O
InChI
InChI=1S/C27H52N3O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-35-20-16-21-37-38(33,34)24-36-25(23-31)22-30-18-17-26(28)29-27(30)32/h17-18,25,31H,2-16,19-24H2,1H3,(H,33,34)(H2,28,29,32)/t25-/m0/s1
Molecular Formula
C27H52N3O7P
HBD / HBA
3 / 7
Döndürülebilir Bağlar
26
Ağır Atomlar
38
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
An oral antiviral medication used for the treatment of human smallpox disease caused by variola virus. It is a lipid conjugate of cidofovir that improves oral bioavailability while reducing kidney toxicity associated with cidofovir itself. It is considered a medical countermeasure for bioterrorism-related smallpox exposure.
Yes, Brincidofovir is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL203321. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 483477. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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