Bromisovalum
A brominated sedative and hypnotic agent that was used historically to treat anxiety and insomnia. It belongs to the bromide-containing compounds that were widely used before benzodiazepines became available. It is no longer in clinical use due to the risk of bromism with prolonged administration and the availability of safer alternatives.
Moleküler Ağırlık
223,0700 g/mol
LogP
1,10
TPSA
72,20 Ų
Lipinski RO5
Geçer
Etki Mekanizması
Enhances the effect of gamma-aminobutyric acid (GABA) at GABA-A receptors by binding to an allosteric site and increasing the frequency of chloride ion channel opening. This produces anxiolytic, sedative, hypnotic, and anticonvulsant effects.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Enhances the effect of gamma-aminobutyric acid (GABA) at GABA-A receptors by binding to an allosteric site and increasing the frequency of chloride ion channel opening. This produces anxiolytic, sedative, hypnotic, …
2D Yapı
Cite this structure
Embed this structure
SMILES
CC(C)C(Br)C(=O)NC(N)=O
InChI
InChI=1S/C6H11BrN2O2/c1-3(2)4(7)5(10)9-6(8)11/h3-4H,1-2H3,(H3,8,9,10,11)
Molecular Formula
C6H11BrN2O2
HBD / HBA
2 / 2
Döndürülebilir Bağlar
2
Ağır Atomlar
11
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
A brominated sedative and hypnotic agent that was used historically to treat anxiety and insomnia. It belongs to the bromide-containing compounds that were widely used before benzodiazepines became available. It is no longer in clinical use due to the risk of bromism with prolonged administration and the availability of safer alternatives.
Enhances the effect of gamma-aminobutyric acid (GABA) at GABA-A receptors by binding to an allosteric site and increasing the frequency of chloride ion channel opening. This produces anxiolytic, sedative, hypnotic, and anticonvulsant effects.
Yes, Bromisovalum is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1515611. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 2447. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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