Broxyquinoline
An antimicrobial compound with activity against bacteria, fungi, and protozoa, used historically as an intestinal antiseptic for traveler's diarrhea and intestinal infections. It is a halogenated hydroxyquinoline derivative. Its use has declined due to safety concerns seen with related compounds in the same chemical class.
Moleküler Ağırlık
302,9500 g/mol
LogP
3,20
TPSA
33,10 Ų
Lipinski RO5
Geçer
Etki Mekanizması
Disrupts microbial cell membranes and denatures proteins on contact, producing rapid broad-spectrum antimicrobial activity on skin and wound surfaces.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Disrupts microbial cell membranes and denatures proteins on contact, producing rapid broad-spectrum antimicrobial activity on skin and wound surfaces.
2D Yapı
Cite this structure
Embed this structure
SMILES
Oc1c(Br)cc(Br)c2cccnc12
InChI
InChI=1S/C9H5Br2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H
Molecular Formula
C9H5Br2NO
HBD / HBA
1 / 2
Döndürülebilir Bağlar
0
Ağır Atomlar
13
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
An antimicrobial compound with activity against bacteria, fungi, and protozoa, used historically as an intestinal antiseptic for traveler's diarrhea and intestinal infections. It is a halogenated hydroxyquinoline derivative. Its use has declined due to safety concerns seen with related compounds in the same chemical class.
Disrupts microbial cell membranes and denatures proteins on contact, producing rapid broad-spectrum antimicrobial activity on skin and wound surfaces.
Yes, Broxyquinoline is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL223448. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 2453. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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