Cefmetazole

CHEMBL1201195 Phase 4 Onaylandı Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

471.5 g/mol

LogP

-0.6

Phase

4

A cephamycin-type beta-lactam antibiotic with activity against anaerobic bacteria in addition to gram-positive and gram-negative aerobic organisms. It is used primarily for intra-abdominal, pelvic, and skin infections requiring anaerobic coverage. It also contains the N-methylthiotetrazole group and should be used cautiously with alcohol.

Moleküler Ağırlık

471,5000 g/mol

LogP

-0,60

TPSA

239,00 Å²

Lipinski RO5

Geçer

Etki Mekanizması

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), preventing transpeptidation and cross-linking of peptidoglycan chains. This weakens the bacterial cell wall, leading to osmotic lysis and cell death.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mekanizma

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), preventing transpeptidation and cross-linking of peptidoglycan chains. This weakens the bacterial cell wall, leading to osmotic lysis and cell …

2D Yapı

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SMILES

CO[C@@]1(NC(=O)CSCC#N)C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CS[C@@H]21

InChI

InChI=1S/C15H17N7O5S3/c1-21-14(18-19-20-21)30-6-8-5-29-13-15(27-2,17-9(23)7-28-4-3-16)12(26)22(13)10(8)11(24)25/h13H,4-7H2,1-2H3,(H,17,23)(H,24,25)/t13-,15+/m1/s1

Molecular Formula

C15H17N7O5S3

HBD / HBA

2 / 12

Döndürülebilir Bağlar

9

Ağır Atomlar

30

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

A cephamycin-type beta-lactam antibiotic with activity against anaerobic bacteria in addition to gram-positive and gram-negative aerobic organisms. It is used primarily for intra-abdominal, pelvic, and skin infections requiring anaerobic coverage. It also contains the N-methylthiotetrazole group and should be used cautiously with alcohol.

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), preventing transpeptidation and cross-linking of peptidoglycan chains. This weakens the bacterial cell wall, leading to osmotic lysis and cell death.

Yes, Cefmetazole is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201195. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 42008. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Formül: C15H17N7O5S3

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.