Ceftizoxime Sodium
The sodium salt form of ceftizoxime, used intravenously for the treatment of serious infections including pelvic inflammatory disease and certain types of meningitis. It provides the same broad-spectrum coverage as the parent compound with good activity against anaerobes. Standard precautions regarding cephalosporin hypersensitivity apply.
Moleküler Ağırlık
405,4000 g/mol
TPSA
204,00 Ų
Etki Mekanizması
Disrupts bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting the final transpeptidation step of peptidoglycan synthesis. The resulting cell wall defects cause osmotic instability and bacteriolysis.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Disrupts bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting the final transpeptidation step of peptidoglycan synthesis. The resulting cell wall defects cause osmotic instability and bacteriolysis.
2D Yapı
Cite this structure
Embed this structure
SMILES
CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)[O-])=CCS[C@H]12)c1csc(N)n1.[Na+]
InChI
InChI=1S/C13H13N5O5S2.Na/c1-23-17-7(5-4-25-13(14)15-5)9(19)16-8-10(20)18-6(12(21)22)2-3-24-11(8)18;/h2,4,8,11H,3H2,1H3,(H2,14,15)(H,16,19)(H,21,22);/q;+1/p-1/b17-7-;/t8-,11-;/m1./s1
Molecular Formula
C13H12N5NaO5S2
HBD / HBA
2 / 10
Döndürülebilir Bağlar
5
Ağır Atomlar
26
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
The sodium salt form of ceftizoxime, used intravenously for the treatment of serious infections including pelvic inflammatory disease and certain types of meningitis. It provides the same broad-spectrum coverage as the parent compound with good activity against anaerobes. Standard precautions regarding cephalosporin hypersensitivity apply.
Disrupts bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting the final transpeptidation step of peptidoglycan synthesis. The resulting cell wall defects cause osmotic instability and bacteriolysis.
Yes, Ceftizoxime Sodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201019. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 23663938. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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