Chlophedianol Hydrochloride
The hydrochloride salt of chlophedianol is used as a cough suppressant in over-the-counter combination formulations. It shares the centrally acting antitussive mechanism of the parent compound. It is sometimes combined with antihistamines or decongestants for broader cold and allergy symptom relief.
Moleküler Ağırlık
326,3000 g/mol
TPSA
23,50 Ų
Etki Mekanizması
Competitively blocks histamine H1 receptors on effector cells, preventing histamine-mediated vasodilation, increased vascular permeability, bronchoconstriction, and pruritus. First-generation agents also cross the blood-brain barrier, causing sedation.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Competitively blocks histamine H1 receptors on effector cells, preventing histamine-mediated vasodilation, increased vascular permeability, bronchoconstriction, and pruritus. First-generation agents also cross the blood-brain barrier, causing sedation.
2D Yapı
Cite this structure
Embed this structure
SMILES
CN(C)CCC(O)(c1ccccc1)c1ccccc1Cl.Cl
InChI
InChI=1S/C17H20ClNO.ClH/c1-19(2)13-12-17(20,14-8-4-3-5-9-14)15-10-6-7-11-16(15)18;/h3-11,20H,12-13H2,1-2H3;1H
Molecular Formula
C17H21Cl2NO
HBD / HBA
2 / 2
Döndürülebilir Bağlar
5
Ağır Atomlar
21
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
The hydrochloride salt of chlophedianol is used as a cough suppressant in over-the-counter combination formulations. It shares the centrally acting antitussive mechanism of the parent compound. It is sometimes combined with antihistamines or decongestants for broader cold and allergy symptom relief.
Competitively blocks histamine H1 receptors on effector cells, preventing histamine-mediated vasodilation, increased vascular permeability, bronchoconstriction, and pruritus. First-generation agents also cross the blood-brain barrier, causing sedation.
Yes, Chlophedianol Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200972. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 83813. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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