Cinchophen
An early analgesic and uricosuric compound derived from quinoline, historically used to treat gout and arthritis but withdrawn from clinical use due to severe hepatotoxicity, including cases of fatal liver failure. It represents an important historical lesson in drug safety monitoring. It is no longer used in medicine.
Moleküler Ağırlık
249,2600 g/mol
LogP
3,40
TPSA
50,20 Ų
Lipinski RO5
Geçer
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D Yapı
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SMILES
O=C(O)c1cc(-c2ccccc2)nc2ccccc12
InChI
InChI=1S/C16H11NO2/c18-16(19)13-10-15(11-6-2-1-3-7-11)17-14-9-5-4-8-12(13)14/h1-10H,(H,18,19)
Molecular Formula
C16H11NO2
HBD / HBA
1 / 3
Döndürülebilir Bağlar
2
Ağır Atomlar
19
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
An early analgesic and uricosuric compound derived from quinoline, historically used to treat gout and arthritis but withdrawn from clinical use due to severe hepatotoxicity, including cases of fatal liver failure. It represents an important historical lesson in drug safety monitoring. It is no longer used in medicine.
Yes, Cinchophen is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL348000. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 8593. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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