Clindamycin Phosphate
A phosphate ester prodrug of clindamycin used topically for acne and vaginosis, or intravenously for serious infections. After administration it is converted to active clindamycin, which inhibits bacterial protein synthesis.
Moleküler Ağırlık
505,0000 g/mol
LogP
-1,20
TPSA
174,00 Ų
Lipinski RO5
Geçer
Terapötik Alanlar
Etki Mekanizması
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
2D Yapı
Cite this structure
Embed this structure
SMILES
CCC[C@@H]1C[C@@H](C(=O)N[C@@H]([C@H]2O[C@H](SC)[C@H](OP(=O)(O)O)[C@@H](O)[C@H]2O)[C@H](C)Cl)N(C)C1
InChI
InChI=1S/C18H34ClN2O8PS/c1-5-6-10-7-11(21(3)8-10)17(24)20-12(9(2)19)15-13(22)14(23)16(18(28-15)31-4)29-30(25,26)27/h9-16,18,22-23H,5-8H2,1-4H3,(H,20,24)(H2,25,26,27)/t9-,10+,11-,12+,13+,14-,15+,16+,18+/m0/s1
Molecular Formula
C18H34ClN2O8PS
HBD / HBA
5 / 10
Döndürülebilir Bağlar
9
Ağır Atomlar
31
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
A phosphate ester prodrug of clindamycin used topically for acne and vaginosis, or intravenously for serious infections. After administration it is converted to active clindamycin, which inhibits bacterial protein synthesis.
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Yes, Clindamycin Phosphate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3184512. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 443385. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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