Difluprednate
A potent corticosteroid eye drop used to treat inflammation and pain following eye surgery. It reduces redness, swelling, and discomfort in the eye.
Moleküler Ağırlık
508,5000 g/mol
LogP
3,40
TPSA
107,00 Ų
Lipinski RO5
Geçer
Terapötik Alanlar
Etki Mekanizması
Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.
2D Yapı
Cite this structure
Embed this structure
SMILES
CCCC(=O)O[C@]1(C(=O)COC(C)=O)CC[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C
InChI
InChI=1S/C27H34F2O7/c1-5-6-23(34)36-26(22(33)14-35-15(2)30)10-8-17-18-12-20(28)19-11-16(31)7-9-24(19,3)27(18,29)21(32)13-25(17,26)4/h7,9,11,17-18,20-21,32H,5-6,8,10,12-14H2,1-4H3/t17-,18-,20-,21-,24-,25-,26-,27-/m0/s1
Molecular Formula
C27H34F2O7
HBD / HBA
1 / 9
Döndürülebilir Bağlar
8
Ağır Atomlar
36
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
A potent corticosteroid eye drop used to treat inflammation and pain following eye surgery. It reduces redness, swelling, and discomfort in the eye.
Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.
Yes, Difluprednate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201749. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 443936. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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