Edrophonium

CHEMBL1104 Phase 4 Onaylandı Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
166.2 g/mol
LogP
1.8
Phase
4

A short-acting cholinesterase inhibitor used to diagnose myasthenia gravis and to reverse neuromuscular blockade after surgery. It temporarily increases the availability of acetylcholine at nerve-muscle junctions.

Moleküler Ağırlık

166,2400 g/mol

LogP

1,80

TPSA

20,20 Ų

Lipinski RO5

Geçer

Etki Mekanizması

Blocks neuromuscular transmission at the motor end plate by competing with acetylcholine for nicotinic receptor binding sites, producing skeletal muscle relaxation and paralysis.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mekanizma

Blocks neuromuscular transmission at the motor end plate by competing with acetylcholine for nicotinic receptor binding sites, producing skeletal muscle relaxation and paralysis.

2D Yapı

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SMILES

CC[N+](C)(C)c1cccc(O)c1

InChI

InChI=1S/C10H15NO/c1-4-11(2,3)9-6-5-7-10(12)8-9/h5-8H,4H2,1-3H3/p+1

Molecular Formula

C10H16NO+

HBD / HBA

1 / 1

Döndürülebilir Bağlar

2

Ağır Atomlar

12

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

A short-acting cholinesterase inhibitor used to diagnose myasthenia gravis and to reverse neuromuscular blockade after surgery. It temporarily increases the availability of acetylcholine at nerve-muscle junctions.

Blocks neuromuscular transmission at the motor end plate by competing with acetylcholine for nicotinic receptor binding sites, producing skeletal muscle relaxation and paralysis.

Yes, Edrophonium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1104. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 3202. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Tıbbi Sorumluluk Reddi

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.