Entacapone
This medication works by blocking an enzyme that breaks down levodopa, allowing more of it to reach the brain and control Parkinson's disease symptoms. It is always used together with levodopa and carbidopa.
Moleküler Ağırlık
305,2900 g/mol
LogP
2,10
TPSA
130,00 Ų
Lipinski RO5
Geçer
Terapötik Alanlar
Etki Mekanizması
Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.
2D Yapı
Cite this structure
Embed this structure
SMILES
CCN(CC)C(=O)/C(C#N)=C/c1cc(O)c(O)c([N+](=O)[O-])c1
InChI
InChI=1S/C14H15N3O5/c1-3-16(4-2)14(20)10(8-15)5-9-6-11(17(21)22)13(19)12(18)7-9/h5-7,18-19H,3-4H2,1-2H3/b10-5+
Molecular Formula
C14H15N3O5
HBD / HBA
2 / 6
Döndürülebilir Bağlar
4
Ağır Atomlar
22
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
This medication works by blocking an enzyme that breaks down levodopa, allowing more of it to reach the brain and control Parkinson's disease symptoms. It is always used together with levodopa and carbidopa.
Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.
Yes, Entacapone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL953. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5281081. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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