Epinastine Hydrochloride

CHEMBL1200491 Phase 4 Onaylandı Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

285.8 g/mol

LogP

—

Phase

4

The hydrochloride salt form of epinastine, this ophthalmic antihistamine blocks histamine in the eye to relieve allergy-related itching and redness. The salt form ensures stability in eye drop formulations.

Moleküler Ağırlık

285,7700 g/mol

TPSA

41,60 Å²

Etki Mekanizması

Competitively blocks histamine H1 receptors on effector cells, preventing histamine-mediated vasodilation, increased vascular permeability, bronchoconstriction, and pruritus. First-generation agents also cross the blood-brain barrier, causing sedation.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mekanizma

Competitively blocks histamine H1 receptors on effector cells, preventing histamine-mediated vasodilation, increased vascular permeability, bronchoconstriction, and pruritus. First-generation agents also cross the blood-brain barrier, causing sedation.

2D Yapı

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SMILES

Cl.NC1=NCC2c3ccccc3Cc3ccccc3N12

InChI

InChI=1S/C16H15N3.ClH/c17-16-18-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)19(15)16;/h1-8,15H,9-10H2,(H2,17,18);1H

Molecular Formula

C16H16ClN3

HBD / HBA

2 / 1

Döndürülebilir Bağlar

0

Ağır Atomlar

20

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

The hydrochloride salt form of epinastine, this ophthalmic antihistamine blocks histamine in the eye to relieve allergy-related itching and redness. The salt form ensures stability in eye drop formulations.

Competitively blocks histamine H1 receptors on effector cells, preventing histamine-mediated vasodilation, increased vascular permeability, bronchoconstriction, and pruritus. First-generation agents also cross the blood-brain barrier, causing sedation.

Yes, Epinastine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200491. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 157313. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Formül: C16H16ClN3

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.

Epinastine Hydrochloride

Etki Mekanizması

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Yapı

Cite this structure

Embed this structure

No targets recorded

No interactions recorded

No side effects recorded

Sıkça Sorulan Sorular

References & Data Sources

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