Estetrol
This naturally occurring estrogen, produced in significant amounts only during pregnancy, has selective activity in different tissues and is used in combination oral contraceptives. It provides effective pregnancy prevention with a targeted hormonal profile.
Moleküler Ağırlık
304,4000 g/mol
LogP
1,50
TPSA
80,90 Ų
Lipinski RO5
Geçer
Terapötik Alanlar
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D Yapı
Cite this structure
Embed this structure
SMILES
C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1[C@@H](O)[C@@H](O)[C@@H]2O.O
InChI
InChI=1S/C18H24O4.H2O/c1-18-7-6-12-11-5-3-10(19)8-9(11)2-4-13(12)14(18)15(20)16(21)17(18)22;/h3,5,8,12-17,19-22H,2,4,6-7H2,1H3;1H2/t12-,13-,14-,15-,16-,17+,18+;/m1./s1
Molecular Formula
C18H24O4
HBD / HBA
4 / 4
Döndürülebilir Bağlar
0
Ağır Atomlar
22
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
This naturally occurring estrogen, produced in significant amounts only during pregnancy, has selective activity in different tissues and is used in combination oral contraceptives. It provides effective pregnancy prevention with a targeted hormonal profile.
Yes, Estetrol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL6068423. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 27125. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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